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In contrast, UC is characterized by persistent inflammation of the mucosal and submucosal layers of the colon, with the initial manifestation of the disease typically occurring in the rectum and subsequently extending gradually along the colon

Owing to the pronounced heterogeneity of IBD, biologics and small-molecule agents elicit highly variable responses, with approximately 3040% of patients experiencing primary or secondary loss of response [17]

Shafabakhsh R, Mobini M, Raygan F, Aghadavod E, Ostadmohammadi V, Amirani E, et al

Western populations are uncommonly affected by severe niacin deficiency that results in pellagra, but individuals at risk of pellagra may have suboptimal niacin intake, such as cancer patients and those exposed to genotoxic agents such as ionizing radiation, ultraviolet radiation, and alkylating agents [444]

Washing lipoaspirate improves fat graft survival in nude mice